Sitting with her was Kristin Knouse, one of the institutes young, talented researchers who, during this conversation, could barely suppress her nerves. There were only a limited number of positive references to him, citing his scientific brilliance and leadership of an intense, hard-charging lab bent on breakthrough findings. His move came after three senior MIT officials recommended revoking his tenure. By early 2021, as the diversity, equity, and inclusion survey and a pair of other complaints came into HR around the same time, Lehmann and other administrators began to suspect one of Whiteheads top labs may have a toxic underside. He told the Globe that he was stunned by the harsh judgments of the report, believing that after 24 years running one of the top labs at Whitehead, he would be given a chance to defend himself against the reports conclusions. He told the Globe he had no idea any of the survey complaints were focused on him. "A mischaracterization of an informal workplace that is populated by people with MDs and PhDs who are in their 20s and 30s who are, you know, underpaid and together long hours and it's just not a viper pit of sexual harassment the way that the Whitehead statement made it sound," he said. She . Her PhD research in David Sabatini's lab at the Whitehead Institute, MIT focused on the mechanisms of amino acid sensing by the mTOR pathway. On March 1, 2022, Sabatini took a train to Manhattan. She said that Sabatini, at a work retreat, asked her to pick between two male postdocs and was once asked by him whether she was romantically interested in his brother, Bernardo, a Harvard neuroscience professor. Knouses allegation, though initially vague, landed like a ticking time bomb in Lehmanns lap. They published scientific papers at a prolific pace, more than 200 since he launched his lab in 1997. There was a great esprit de corps in the lab, said one member who was there in the years leading up to Sabatinis fall. It was not about jealousy or disappointed hopes, according to friends who spoke to her then. Thats really really important. Then he added: By the way, its my wife and I who made this decision. Ackmans wife, Neri Oxman, a designer and former MIT professor, serves as a co-trustee of the Pershing Square Foundation. But the investigators said Sabatini and Knouse both violated Whitehead policies barring all principal investigators from having a romantic or sexual relationship with any Whitehead employee, even of the same high level. That panel voted unanimously to affirm the recommendation of the President to terminate David Sabatini as a Member of the Institute on Aug. 20, 2021 unless her recommendation changes.. Percentage of administrative and support staff who said they felt comfortable reporting offensive comments to leadership, but only 11 percent of scientific researchers felt the same, suggesting a more tenuous connection to the institution. Among them was a white male graduate student who said that Sabatini tolerated a particular visiting scientist who routinely made sexist and racist remarks. On social media, people in and outside academia either railed against Sabatini or fiercely defended him. (Erin Clark/Globe Staff), The Sjberg Prize 2020 went to David Sabatini (right) as well as Michael N. Hall from the Biozentrum in Basel, Switzerland. A focus on improving workplace environments and weeding out sexual harassment was happening at institutions around the country at this point after a mandate from a major government grant source, the National Institutes of Health (NIH), to "develop and implement policies and practices that foster a harassment-free environment" or risk losing funding. The primary source of offensive language was the institutes most powerful players, its principal investigators, the survey said. In the meeting with Lehmann that day, Knouse found it hard to contemplate, much less talk about something so painful, so confusing, and so long a secret. Ackmans move sends the message that some high-profile and ethical people are willing to support David Sabatini re-engaging his brilliant career as a scientist and mentor of other scientists, despite the risk that by doing so they themselves will be falsely attacked, says Jeffrey Flier, an endocrinologist at Harvard Medical School and former dean there. As many of you will know, David Sabatini, "mTORman" and a former star of cancer, ageing and diabetes research, has been sacked by the Whitehead Institute and HHMI for sexual harassment. At the time, Sabatini ran a lab of nearly 40 people and was an HHMI investigator and the lead scientist on five National Institutes of Health grants totaling nearly $2 million. On Dec. 10, 2020, Whiteheads diversity, equity, and inclusion survey, the culture-challenging initiative launched by Lehmann, dropped in Knouses e-mail box, as it did for more than 500 other employees at Whitehead. He is interested in understanding how the mTOR pathway . Sign up to receive Spotlight reports and special projects in your inbox. In the face of fierce backlash from faculty members and students at New York University, a biologist who is accused of past sexual harassment will not . Sabatini later would tell the Globe that investigators had asked him about incidents in the past that he simply couldnt immediately recall. Sabatinis hopes for a second chance evaporated. | In a counterclaim filing against MIT professor David Sabatini, his former mentee and Whitehead Institute colleague alleges he "coerced" her into sex and led a "highly sexualized" lab. She couldnt know it at the time, but the survey would, in tandem with other concerns voiced by staff, have seismic consequences. The investigative report resounded like a thunderclap. Sabatini, who joined the Institute in 1997 as a Whitehead Fellow, was named an Associate Member at Whitehead and an Assistant Professor in the biology department at MIT. A lawyer for Kristin Knouse, the then-Whitehead biologist whose relationship with Sabatini sparked his downfall, declined to comment. To reach the Spotlight Team staff members who worked on this piece, please write to [emailprotected] or call 617-929-7483 or individually at [emailprotected], [emailprotected] and [emailprotected]. While most addressed Whiteheads work culture generally, three anonymous respondents singled out Sabatini. (Dieu-Nalio Chry/The New York Times), Kristin Knouse appeared at a Suffolk Superior Court hearing in December 2022 during which her lawyers sought to dismiss Sabatini's defamation case against her, and his lawyers also sought to dismiss her counter-claim for sexual harassment. Still, she works hard not to let the controversy or the ongoing court cases distract her from lab work. Note: Text exchanges between individuals in this story are animated. AAAS is a partner of HINARI, AGORA, OARE, CHORUS, CLOCKSS, CrossRef and COUNTER. Please make a tax-deductible gift today. Complaint The complaint was filed on October 20, 2021. We sat down with Spinelli to learn more about her and her experiences in and out of the lab. 2023 American Association for the Advancement of Science. He said that after hearing comments from members about their interviews with investigators, he had merely asked them whether they thought the probe was really about lab culture. David Sabatini, forced out of three institutions, appears to have support from NYU medical school dean and a New York billionaire philanthropist. Awards and money were pouring in. The Foundation for the National Institutes of Health (FNIH) has selected David M. Sabatini, M.D., Ph.D., to receive its fifth annual Lurie Prize in Biomedical Sciences for discovery of the mTOR (mechanistic target of rapamycin) cellular pathway as a key regulator of growth and metabolism in response to nutrients. There were good reasons why it seemed unthinkable for Knouse to leave Whitehead, and to name Sabatini as the root of her growing pain. He said he banked on his own sense of what was true and on his trust in his colleagues to put the complaints in proper perspective. But the complaints of the two scientists to Whitehead human resources both well-respected and more senior than Knouse carried credibility with administrators and had legal impact. Lehmann would not comment on whether Whitehead leadership had considered a less confrontational legal option anything short of a full investigation by a law firm. Ive been here forever. (Pat Greenhouse/Globe Staff), David Sabatini sat on the doorsteps at his home in Cambridge last September. Knouses resentment of Sabatini intensified when she summoned the nerve, sometime in 2019, to open up about her feelings to a handful of other women at Whitehead. The former dean of Harvard Medical School, Jeffrey Flier, asked on Twitter, shortly after Sabatinis ousting, if Sabatini had received a fair hearing. Given Sabatinis scientific skill, she said she believed he could be valuable at NYU, but only if leadership at the school felt comfortable after reviewing the allegations. He was fired in August of 2021, after which most of his professional connections quickly dried up. This place where lab experiments once hummed, where scientists hoped to break new ground and find cures for cancer, diabetes, and Parkinsons, went quiet. It was a stunning step; it made no sense. It's the only board he wasn't removed from amid the controversy, according to Sabatini who was stripped of millions of dollars in research grants and esteemed positions when the Whitehead allegations became public. He joined OU in 1989 and is currently Director of the Water Technologies for Emerging Regions (WaTER) Center and Associate Director of the Institute for Applied Surfactant Reseach. . So how am I supposed to get my life back other than to get the truth out there?. Soon after the faculty position leaked in an industry publication, NYU students and faculty staged a. May 4, 2022. He said nothing, just watched the bird hop away, free. [And] Mr. Ackman would like to set us back by decades. She was very worried about Kristin, Weis said. With this letter, we wish to affirm that we never experienced or observed an abusive lab culture or a sexualized lab environment, and we did not witness sexual harassment," t. The Massachusetts Institute of Technology Whitehead Institute. The independent report pointedly said it did not aim to determine whether the sexual relationship confirmed by Sabatini and Knouse was consensual. A former member of his lab told the Globe he believed Sabatini had reached out to other lab members out of concern, after being told that some were freaking out.. Some held signs with slogans such as "Title IX over Sabatini.". A renowned Massachusetts Institute of . She told human resource officials that Sabatini showed more personal attention to attractive lab members and that female trainees deliberately flirt a little with Sabatini because they believe it will boost their careers. This followed a bombshell report from Science this week indicating that NYU's Grossman . He doesnt care because he doesnt have to worry about the graduate students whose career may be ended by a powerful person.. Sabatini's research focuses on, at the biochemical, cellular and organismal level, a signaling network called the mTOR pathway. "How are you going make change if you don't follow the rules that were written to make change," Hopkins opined. (Knouse declined several previous requests for interviews, but ultimately consented on the condition that her lawyers be present and that she would not publicly discuss her relationship with Sabatini due to his pending defamation case against her.). My life was 100 percent destroyed, he told the Globe. His lab has focused significant efforts on the mTOR pathway. AAAS is a partner of HINARI, AGORA, OARE, CHORUS, CLOCKSS, CrossRef and COUNTER. In late April, some 200 students and faculty from NYUs Grossman School of Medicine poured into the streets in a high-profile demonstration against the schools interest in Sabatini. Dr. Sabatini, 54, is a prominent biologist, best known for his discovery of the mTOR protein, which regulates cell growth in animals, as a graduate student. His marriage to Pernas did not survive. When some of the women got together socially, all kinds of subjects were on the table, including their uncomfortable experiences involving Sabatini and the offensive edge of some of the discourse in his lab, according to interviews and texts reviewed by the Globe. David Sabatini lab's 2021 gender breakdown Employees (39) Male 59% Female 41% Post-doc and graduate students (21) Male 67% Female 33% Source: Whitehead Institute. My father will die before this is cleared up. David Sabatini is David Ross Boyd Professor and Sun Oil Company Endowed Chair of Civil Engineering and Environmental Science at the University of Oklahoma. I mean he legally cannot retaliate but basically he could go on twitter and call me a scorned ex lover then thats out there it cant be unsaid. Knouse had also told them of seemingly contradictory emotions about Sabatini, sometimes apparently wanting more from him, other times complaining about being exploited. There was a fire inside me for this, Knouse told the Globe, in her first of two interviews since her role in the Sabatini controversy became public. Knouse was a graduate student then Whitehead Fellow in 2018 and 2019 at the time of sexual relationship. New York University's Grossman School of Medicine will no longer consider Dr. David Sabatini, a biologist facing accusations of sexual harassment, for a faculty position after news that he was. He also acknowledged to the Globe he showed several of them a sample of the texts Knouse had sent him in early 2020 when she wrote of wanting a deeper relationship with him. Want to subscribe & listen to #ASGCT's Giants of Gene Therapy on your Podcasts app? They also studied the function of novel components of the pathway in mice. After the viewing, Knouse thought to herself, as she recalled to the Globe, It is wrong for me to stay quiet.. He was hearing about some of the complaints for the first time and had never imagined that some of the banter in the lab would lead to a large-scale investigation. NYU was considering offering him a non-tenured position for a trial period, with an out-clause so the school could freely dismiss Sabatini if more derogatory information surfaced. In November, she published a paper in Cell Genomics about her labs development of a novel technology that will allow researchers to investigate the function of every gene in a living mammal. I look forward to setting the record straight and standing up for my integrity.. Ackman said in a tweet that his foundation was looking to secure funding partners to support a new Sabatini lab, linking to the Spotlight team's story that Ackman called an accurate and balanced portrayal of the facts. The groups also started a petition which had gathered over 300 signatures by Thursday afternoon. The law firm hired by Whitehead, Hinckley Allen, assigned three lawyers to investigate the culture of the lab and Sabatinis leadership. Reif added: "The Committee also had significant concerns regarding his unprofessional behavior toward some lab members." . He was a tenured professor at MIT. Meeting at National Renewable Energy Laboratory with rising leaders from the energy sector inspired me that we will meet the low carbon transition head on. 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